As the world’s population is living longer, age-related neurodegenerative diseases are becoming a more significant global issue. Neurodegenerative diseases cause worsening motor, cognitive and autonomic dysfunction over time and reduce functional abilities required for daily living. Compromised motor performance is one of the first and most evident manifestations. In the case of Parkinson’s disease, these impairments are currently evaluated by experts through the use of rating scales. Although this method is widely used by experts worldwide, it includes subjective and error-prone motor examinations that also fail in the characterization of symptoms’ fluctuations. The aim of this study is to evaluate whether artificial intelligence techniques can be used to objectively assess gait impairment in subjects with Parkinson’s disease. This paper presents the results of a cohort of ten subjects, five with a Parkinson’s disease diagnosis at different degrees of severity. We experimentally demonstrate good effectiveness of the proposed system in extracting the main features concerning people’s gait during the standard tests that clinicians use to assess the burden of disease. This system can offer neurologists, through accurate and objective data, a second opinion or a suggestion to reconsider score assignment. Thanks to its simplicity, tactful and non-intrusive approach and clinical-grade accuracy, it can be adopted on an ongoing basis even in environments where people usually live and work.

Using a Video Device and a Deep Learning-Based Pose Estimator to Assess Gait Impairment in Neurodegenerative Related Disorders: A Pilot Study

Romagnoli, Cristian;
2022

Abstract

As the world’s population is living longer, age-related neurodegenerative diseases are becoming a more significant global issue. Neurodegenerative diseases cause worsening motor, cognitive and autonomic dysfunction over time and reduce functional abilities required for daily living. Compromised motor performance is one of the first and most evident manifestations. In the case of Parkinson’s disease, these impairments are currently evaluated by experts through the use of rating scales. Although this method is widely used by experts worldwide, it includes subjective and error-prone motor examinations that also fail in the characterization of symptoms’ fluctuations. The aim of this study is to evaluate whether artificial intelligence techniques can be used to objectively assess gait impairment in subjects with Parkinson’s disease. This paper presents the results of a cohort of ten subjects, five with a Parkinson’s disease diagnosis at different degrees of severity. We experimentally demonstrate good effectiveness of the proposed system in extracting the main features concerning people’s gait during the standard tests that clinicians use to assess the burden of disease. This system can offer neurologists, through accurate and objective data, a second opinion or a suggestion to reconsider score assignment. Thanks to its simplicity, tactful and non-intrusive approach and clinical-grade accuracy, it can be adopted on an ongoing basis even in environments where people usually live and work.
Zanela, Andrea; Schirinzi, Tommaso; Mercuri, Nicola Biagio; Stefani, Alessandro; Romagnoli, Cristian; Annino, Giuseppe; Bonaiuto, Vincenzo; Cerroni, Rocco
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/885630
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