We investigated by a computational model of the basal ganglia system (BGS) the different network effects of deep brain stimulation (DBS) for Parkinson’s disease (PD) in different target sites in the subthalamic nucleus (STN), the globus pallidus pars interna (GPi), and pars externa (GPe). In particular, our focus here is in disclosing possible interpretations of the clinical motor outcomes observed with different stimulation targets based on simulation results.
The clinical outcomes of different targets in deep brain stimulation for Parkinson’s disease: an interpretation based on a computational model
PIRINI, MARCO;ROCCHI, LAURA;PALMERINI, LUCA;CHIARI, LORENZO
2009
Abstract
We investigated by a computational model of the basal ganglia system (BGS) the different network effects of deep brain stimulation (DBS) for Parkinson’s disease (PD) in different target sites in the subthalamic nucleus (STN), the globus pallidus pars interna (GPi), and pars externa (GPe). In particular, our focus here is in disclosing possible interpretations of the clinical motor outcomes observed with different stimulation targets based on simulation results.File in questo prodotto:
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