Meningiomas are the most common primary intracranial tumors. The majority of meningiomas are benign, but they can present different grades of dedifferentiation from grade I to grade III (anaplastic/malignant) that are associated with different outcomes. Radiological surveillance is a valid option for low-grade asymptomatic meningiomas. In other cases, the treatment is usually surgical, aimed at achieving a complete resection. The use of adjuvant radiotherapy is the gold standard for grade III, is debated for grade II and is not generally indicated for radically resected grade I meningiomas. The use of systemic treatments is not standardized. Here we report a review of the literature on the clinical, radiological and molecular characteristics of meningiomas, available treatment strategies and ongoing clinical trials.

Maggio, I., Franceschi, E., Tosoni, A., DI NUNNO, V., Gatto, L., Lodi, R., et al. (2021). Meningioma: Not always a benign tumor. A review of advances in the treatment of meningiomas. CNS ONCOLOGY, 10(2), CNS72-CNS72 [10.2217/cns-2021-0003].

Meningioma: Not always a benign tumor. A review of advances in the treatment of meningiomas

Ilaria Maggio;Enrico Franceschi;Vincenzo Di Nunno;Lidia Gatto;Raffaele Lodi;
2021

Abstract

Meningiomas are the most common primary intracranial tumors. The majority of meningiomas are benign, but they can present different grades of dedifferentiation from grade I to grade III (anaplastic/malignant) that are associated with different outcomes. Radiological surveillance is a valid option for low-grade asymptomatic meningiomas. In other cases, the treatment is usually surgical, aimed at achieving a complete resection. The use of adjuvant radiotherapy is the gold standard for grade III, is debated for grade II and is not generally indicated for radically resected grade I meningiomas. The use of systemic treatments is not standardized. Here we report a review of the literature on the clinical, radiological and molecular characteristics of meningiomas, available treatment strategies and ongoing clinical trials.
2021
Maggio, I., Franceschi, E., Tosoni, A., DI NUNNO, V., Gatto, L., Lodi, R., et al. (2021). Meningioma: Not always a benign tumor. A review of advances in the treatment of meningiomas. CNS ONCOLOGY, 10(2), CNS72-CNS72 [10.2217/cns-2021-0003].
Maggio, Ilaria; Franceschi, Enrico; Tosoni, Alicia; DI NUNNO, Vincenzo; Gatto, Lidia; Lodi, Raffaele; A Brandes, Alba
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/868542
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