Objectives: A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial. Methods: A case-control study was conducted in Italy in 1991-2002. Cases were 1294 men with incident prostate cancer, and controls were 1451 men admitted to hospital for acute non-neoplastic diseases. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using unconditional multiple logistic regression. Results: Compared to the lowest one quintile of dietary calcium intake the OR was 1.18 for the highest, 1.01 for an increment of 622 mg/day of calcium, and 1.29 (95% CI 0.78-2.13) for 2000 mg/day or more of calcium. The OR of prostate cancer for the highest quintile of dietary intake of vitamin D and phosphorus were 1.33 and 1.20 respectively. Conclusions: This study shows no material association of dietary intake of calcium, vitamin D and phosphorus with prostate cancer risk. (c) 2005 Elsevier B.V. All rights reserved.
Dietary intake of calcium,vitamin D, phosphorus and the risk of prostate cancer / Tavani A; Bertuccio P; Bosetti C; Talamini R; Negri E; Franceschi S; Montella M; La Vecchia C. - In: EUROPEAN UROLOGY. - ISSN 0302-2838. - 48:1(2005), pp. 27-33. [10.1016/j.eururo.2005.03.023]
Dietary intake of calcium,vitamin D, phosphorus and the risk of prostate cancer
Negri E;
2005
Abstract
Objectives: A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial. Methods: A case-control study was conducted in Italy in 1991-2002. Cases were 1294 men with incident prostate cancer, and controls were 1451 men admitted to hospital for acute non-neoplastic diseases. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using unconditional multiple logistic regression. Results: Compared to the lowest one quintile of dietary calcium intake the OR was 1.18 for the highest, 1.01 for an increment of 622 mg/day of calcium, and 1.29 (95% CI 0.78-2.13) for 2000 mg/day or more of calcium. The OR of prostate cancer for the highest quintile of dietary intake of vitamin D and phosphorus were 1.33 and 1.20 respectively. Conclusions: This study shows no material association of dietary intake of calcium, vitamin D and phosphorus with prostate cancer risk. (c) 2005 Elsevier B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
