We investigated the influence of anthropometric measures at diagnosis and at different ages on prostate cancer risk using an Italian multicentre case-control study conducted between 1991 and 2002 of 1294 histologically confirmed cases and 1451 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Height, weight, body mass index (BMI), waist-to-hip ratio, lean body mass 1 year before diagnosis/interview were not significantly associated with risk. However, a positive association with high BMI at age 30 years was found (odds ratio = 1.2 for BMI greater than or equal to 24.7 vs <22.7) and: for less differentiated prostate cancer, with BMI 1 year before diagnosis/interview. This study supports possible relationships between high body mass in young adulthood, and a tendency to high weight throughout adult life, and the risk of prostate cancer. (C) 2004 Cancer Research UK.
Prostate cancer and body size at different ages: an Italian multicentre case - control study / Dal Maso L; Zucchetto A; La Vecchia C; Montella M; Conti E; Canzonieri V; Talamini R; Tavani A; Negri E; Garbeglio A; Franceschi S. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - 90:11(2004), pp. 2176-2180. [10.1038/sj.bjc.6601859]
Prostate cancer and body size at different ages: an Italian multicentre case - control study
Negri E;
2004
Abstract
We investigated the influence of anthropometric measures at diagnosis and at different ages on prostate cancer risk using an Italian multicentre case-control study conducted between 1991 and 2002 of 1294 histologically confirmed cases and 1451 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Height, weight, body mass index (BMI), waist-to-hip ratio, lean body mass 1 year before diagnosis/interview were not significantly associated with risk. However, a positive association with high BMI at age 30 years was found (odds ratio = 1.2 for BMI greater than or equal to 24.7 vs <22.7) and: for less differentiated prostate cancer, with BMI 1 year before diagnosis/interview. This study supports possible relationships between high body mass in young adulthood, and a tendency to high weight throughout adult life, and the risk of prostate cancer. (C) 2004 Cancer Research UK.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.