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EnglishPurpose: To investigate the association between food and nutrient intake, occupational and leisure-time physical activity, and body mass index and breast cancer risk by estrogen receptor (ER) and progesterone receptor (PR) status. Methods: We analyzed data from a hospital-based case-control study conducted between 1991 and 1994 in Italy, including 1075 women with incident breast cancer and 1477 controls. Results: The associations with breast cancer risk were similar according to ER status for all risk factors considered. In particular, significant reduced risk of ER- and ER+ breast cancers were observed for raw vegetables (multivariate odds ratio, OR, for high vs low consumption: 0.6 and 0.7, respectively) and for polyunsaturated fats (OR: 0.6 and 0.7, respectively). No significant heterogeneous risk estimates were observed for combinations of ER and PR status. Conclusions: Our study does not suggest major differences risk for various dietary and lifestyle factors according to ER and PR breast cancer subtypes.
| Titolo: | Nutritional factors, physical activity, and breast cancer by hormonal receptor status | |
| Autore/i: | V. Rosato; P. Bertuccio; C. Bosetti; E. Negri; V. Edefonti; M. Ferraroni; A. Decarli; R. Talamini; L. Dal Maso; F. Falcini; M. Montella; S. Franceschi; C. La Vecchia | |
| Autore/i Unibo: | ||
| Anno: | 2013 | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.breast.2013.04.004 | |
| Abstract: | Purpose: To investigate the association between food and nutrient intake, occupational and leisure-time physical activity, and body mass index and breast cancer risk by estrogen receptor (ER) and progesterone receptor (PR) status. Methods: We analyzed data from a hospital-based case-control study conducted between 1991 and 1994 in Italy, including 1075 women with incident breast cancer and 1477 controls. Results: The associations with breast cancer risk were similar according to ER status for all risk factors considered. In particular, significant reduced risk of ER- and ER+ breast cancers were observed for raw vegetables (multivariate odds ratio, OR, for high vs low consumption: 0.6 and 0.7, respectively) and for polyunsaturated fats (OR: 0.6 and 0.7, respectively). No significant heterogeneous risk estimates were observed for combinations of ER and PR status. Conclusions: Our study does not suggest major differences risk for various dietary and lifestyle factors according to ER and PR breast cancer subtypes. | |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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