Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
Negri E, La Vecchia C, Franceschi S (2002). Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study. EUROPEAN JOURNAL OF CLINICAL NUTRITION, 56(2), 166-170 [10.1038/sj.ejcn.1601].
Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study
Negri E;
2002
Abstract
Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
