To evaluate the potential variability of Manganese (Mn2+) in commercial pineapple juice (PJ) produced in diferent years and to identify the optimal Mn2+ concentration in the correct amount of PJ to be administered prior to Magnetic Resonance Cholangiopancreatography (MRCP) in order to suppress the gastroduodenal (GD) liquid signal. The Mn2+ concentration in PJ produced in diferent years was defned using Atomic Absorption Spectrometry. The optimal Mn2+ concentration and the amount of PJ, were estimated in an in-vitro analysis, and were then prospectively tested in a population of patients who underwent MRCP. The results were compared with those achieved with the previous standard amount of PJ used in a similar population. The concentrations of Mn2+ in commercial PJ produced in diferent years did not difer. A total amount of 150 ml (one glass) of PJ having a high Mn2+ content (2.37 mg/dl) was sufcient for the suppression of the GD liquid signal, despite the additional dilution caused by GD liquids since it led to a fnal concentration of Mn2+ of 0.5–1.00 mg/dl. The optimized single-dose oral administration of 150 ml (approximately one glass) of PJ having a high Mn2+ concentration prior to MRCP was adequate to guarantee the correct amount of Mn2+ to suppress the GD signal

Optimization of pineapple juice amount used as a negative oral contrast agent in magnetic resonance cholangiopancreatography

Renzulli, Matteo
Primo
;
Caretti, Daniele;Pettinari, Irene;Biselli, Maurizio;Brocchi, Stefano;Sergenti, Alessandro;Brandi, Nicolò;Golfieri, Rita
2022

Abstract

To evaluate the potential variability of Manganese (Mn2+) in commercial pineapple juice (PJ) produced in diferent years and to identify the optimal Mn2+ concentration in the correct amount of PJ to be administered prior to Magnetic Resonance Cholangiopancreatography (MRCP) in order to suppress the gastroduodenal (GD) liquid signal. The Mn2+ concentration in PJ produced in diferent years was defned using Atomic Absorption Spectrometry. The optimal Mn2+ concentration and the amount of PJ, were estimated in an in-vitro analysis, and were then prospectively tested in a population of patients who underwent MRCP. The results were compared with those achieved with the previous standard amount of PJ used in a similar population. The concentrations of Mn2+ in commercial PJ produced in diferent years did not difer. A total amount of 150 ml (one glass) of PJ having a high Mn2+ content (2.37 mg/dl) was sufcient for the suppression of the GD liquid signal, despite the additional dilution caused by GD liquids since it led to a fnal concentration of Mn2+ of 0.5–1.00 mg/dl. The optimized single-dose oral administration of 150 ml (approximately one glass) of PJ having a high Mn2+ concentration prior to MRCP was adequate to guarantee the correct amount of Mn2+ to suppress the GD signal
Renzulli, Matteo; Caretti, Daniele; Pettinari, Irene; Biselli, Maurizio; Brocchi, Stefano; Sergenti, Alessandro; Brandi, Nicolò; Golfieri, Rita
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/852191
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