Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronchitis is yet not well defined. Early intermittent, self-administered nebulization of tissue plasminogen activator was found to be effective in preventing deterioration of acute respiratory symptoms in a patient with primary ciliary dyskinesia and recurrent cast formation. Further investigation into new therapeutic strategies for this devastating disease is advocated. © 2014 Colaneri et al.; licensee BioMed Central Ltd.

Colaneri M., Quarti A., Pozzi M., Gasparini S., Carloni I., De Benedictis F.M. (2014). Management of plastic bronchitis with nebulized tissue plasminogen activator: Another brick in the wall. THE ITALIAN JOURNAL OF PEDIATRICS, 40(1), 1-4 [10.1186/1824-7288-40-18].

Management of plastic bronchitis with nebulized tissue plasminogen activator: Another brick in the wall

Quarti A.
Secondo
Conceptualization
;
2014

Abstract

Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronchitis is yet not well defined. Early intermittent, self-administered nebulization of tissue plasminogen activator was found to be effective in preventing deterioration of acute respiratory symptoms in a patient with primary ciliary dyskinesia and recurrent cast formation. Further investigation into new therapeutic strategies for this devastating disease is advocated. © 2014 Colaneri et al.; licensee BioMed Central Ltd.
2014
Colaneri M., Quarti A., Pozzi M., Gasparini S., Carloni I., De Benedictis F.M. (2014). Management of plastic bronchitis with nebulized tissue plasminogen activator: Another brick in the wall. THE ITALIAN JOURNAL OF PEDIATRICS, 40(1), 1-4 [10.1186/1824-7288-40-18].
Colaneri M.; Quarti A.; Pozzi M.; Gasparini S.; Carloni I.; De Benedictis F.M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/850448
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