CENTRAL NERVOUS SYSTEM AND LUNG METASTASIS OF SEBACEOUS EPITHELIOMA IN A DOG

Sebaceous epithelioma is a common canine cutaneous neoplasm characterized by a preponderance of basaloid cells with few well differentiated sebocytes. It is considered a low grade malignancy, as it may occasionally recur at the excision site; the possibility of lymph node metastasis is anecdotally reported, and distant metastases have never been observed. This case report presents the clinical and pathologic features of a sebaceous epithelioma of the upper lip with a highly aggressive behaviour. The patient was a 9-year-old female dachshund that developed local recurrence eleven months after the excision of the primary sebaceous epithelioma and multiple lung and central nervous system metastases five months later. The designation epitheliomatous sebaceous carcinoma has been suggested for aggressive sebaceous epitheliomas, although differential criteria are still to be determined.