Eating seafood has numerous health benefits; however, it constitutes one of the main sources of exposure to several harmful environmental pollutants, both of anthropogenic and natural origin. Among these, methylmercury and polycyclic aromatic hydrocarbons give rise to concerns related to their possible effects on human biology. In the present review, we summarize the results of epidemiological investigations on the genetic component of individual susceptibility to methylmercury and polycyclic aromatic hydrocarbons exposure in humans, and on the effects that these two pollutants have on human epigenetic profiles (DNA methylation). Then, we provide evidence that Mediterranean coastal communities represent an informative case study to investigate the potential impact of methylmercury and polycyclic aromatic hydrocarbons on the human genome and epigenome, since they are characterized by a traditionally high local seafood consumption, and given the characteristics that render the Mediterranean Sea particularly polluted. Finally, we discuss the challenges of a molecular anthropological approach to this topic.

Methylmercury and polycyclic aromatic hydrocarbons in mediterranean seafood: A molecular anthropological perspective / De Giovanni A.; Giuliani C.; Marini M.; Luiselli D.. - In: APPLIED SCIENCES. - ISSN 2076-3417. - ELETTRONICO. - 11:23(2021), pp. 11179.11179-11179.11.206. [10.3390/app112311179]

Methylmercury and polycyclic aromatic hydrocarbons in mediterranean seafood: A molecular anthropological perspective

De Giovanni A.
Primo
;
Giuliani C.
Secondo
;
Luiselli D.
Ultimo
2021

Abstract

Eating seafood has numerous health benefits; however, it constitutes one of the main sources of exposure to several harmful environmental pollutants, both of anthropogenic and natural origin. Among these, methylmercury and polycyclic aromatic hydrocarbons give rise to concerns related to their possible effects on human biology. In the present review, we summarize the results of epidemiological investigations on the genetic component of individual susceptibility to methylmercury and polycyclic aromatic hydrocarbons exposure in humans, and on the effects that these two pollutants have on human epigenetic profiles (DNA methylation). Then, we provide evidence that Mediterranean coastal communities represent an informative case study to investigate the potential impact of methylmercury and polycyclic aromatic hydrocarbons on the human genome and epigenome, since they are characterized by a traditionally high local seafood consumption, and given the characteristics that render the Mediterranean Sea particularly polluted. Finally, we discuss the challenges of a molecular anthropological approach to this topic.
2021
Methylmercury and polycyclic aromatic hydrocarbons in mediterranean seafood: A molecular anthropological perspective / De Giovanni A.; Giuliani C.; Marini M.; Luiselli D.. - In: APPLIED SCIENCES. - ISSN 2076-3417. - ELETTRONICO. - 11:23(2021), pp. 11179.11179-11179.11.206. [10.3390/app112311179]
De Giovanni A.; Giuliani C.; Marini M.; Luiselli D.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/849258
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