A new mild method for protecting alcohols as t-butyl ethers is reported. The reaction proceeds with Mg(ClO4)2 and Boc2O and shows general applicability. The deprotection of t-butyl ethers has also been revisited. Preliminary results indicate the CeCl3â7H2O/NaI system is a very suitable catalyst for their removal.
Titolo: | Unusual and Unexpected Reactivity of t-Butyl Dicarbonate (Boc2O) with Alcohols in the Presence of Magnesium Perchlorate. A New and General Route to t-Butyl Ethers |
Autore/i: | BARTOLI, GIUSEPPE; BOSCO, MARCELLA; LOCATELLI, MANUELA; E. Marcantoni; MELCHIORRE, PAOLO; SAMBRI, LETIZIA |
Autore/i Unibo: | |
Anno: | 2005 |
Rivista: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1021/ol047704o |
Abstract: | A new mild method for protecting alcohols as t-butyl ethers is reported. The reaction proceeds with Mg(ClO4)2 and Boc2O and shows general applicability. The deprotection of t-butyl ethers has also been revisited. Preliminary results indicate the CeCl3â7H2O/NaI system is a very suitable catalyst for their removal. |
Data prodotto definitivo in UGOV: | 2005-10-07 17:36:23 |
Appare nelle tipologie: | 1.01 Articolo in rivista |
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