In recent years, gastric ulceration has been recognised as a common, possibly performance-limiting disease of adult horse. The aim of this study was to compare endoscopic features, histological diagnosis and cytokines’ mRNA (TNF-α, IL-1β, and IL-13) from gastric biopsies. The sample was represented by 11 horses suffering from equine gastric ulcer syndrome and 7 horses with normal histological gastric features. No correlation between endoscopic features and histology (gold standard) was observed. Based on histological diagnosis, in horses affected by equine ulcerative gastric syndrome a significant (p<0.05) increase in cytokines’ mRNA (TNF-α and IL-13) was observed.
PIETRA M., MORINI M., PERFETTI G., SPADARI A., VIGO P., PELI A. (2009). Confronto tra reperti endoscopici, rilievi istologici ed espressione citochinica della mucosa gastrica di cavallo.
Confronto tra reperti endoscopici, rilievi istologici ed espressione citochinica della mucosa gastrica di cavallo
PIETRA, MARCO;MORINI, MARIA;SPADARI, ALESSANDRO;VIGO, PAOLO;PELI, ANGELO
2009
Abstract
In recent years, gastric ulceration has been recognised as a common, possibly performance-limiting disease of adult horse. The aim of this study was to compare endoscopic features, histological diagnosis and cytokines’ mRNA (TNF-α, IL-1β, and IL-13) from gastric biopsies. The sample was represented by 11 horses suffering from equine gastric ulcer syndrome and 7 horses with normal histological gastric features. No correlation between endoscopic features and histology (gold standard) was observed. Based on histological diagnosis, in horses affected by equine ulcerative gastric syndrome a significant (p<0.05) increase in cytokines’ mRNA (TNF-α and IL-13) was observed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
