Diabetic kidney disease (DKD) is a common complication of type 1 and 2 diabetes and often presents during adolescence and young adulthood. Given the growing incidence of both type 1 and type 2 diabetes in children and adolescents, DKD represents a significant public health problem. Acute kidney injury (AKI) in youth with diabetes is strongly associated with risk of DKD development. This review will summarize the epidemiology and pathophysiology of AKI in children with diabetes, the relationship between AKI and DKD, and the potential therapeutic interventions. Finally, we will appraise the impact of the recent COVID-19 infection pandemic on AKI in children with diabetes.
Acute Kidney Injury in Pediatric Diabetic Kidney Disease / Piani F, Reinicke T, Borghi C, Tommerdahl KL, Cara-Fuentes G, Johnson RJ, Bjornstad P. - In: FRONTIERS IN PEDIATRICS. - ISSN 2296-2360. - STAMPA. - 9:(2021), pp. 668033.1-668033.12. [10.3389/fped.2021.668033]
Acute Kidney Injury in Pediatric Diabetic Kidney Disease
Piani FConceptualization
;Borghi CConceptualization
;
2021
Abstract
Diabetic kidney disease (DKD) is a common complication of type 1 and 2 diabetes and often presents during adolescence and young adulthood. Given the growing incidence of both type 1 and type 2 diabetes in children and adolescents, DKD represents a significant public health problem. Acute kidney injury (AKI) in youth with diabetes is strongly associated with risk of DKD development. This review will summarize the epidemiology and pathophysiology of AKI in children with diabetes, the relationship between AKI and DKD, and the potential therapeutic interventions. Finally, we will appraise the impact of the recent COVID-19 infection pandemic on AKI in children with diabetes.| File | Dimensione | Formato | |
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Piani F_Acute Kidney Injury in Pediatric Diabetic Kidney Disease_Front Pediatr_2021.pdf
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