The first perfluoroalkylation reaction of activated arenes (amino-substituted arenes and alkoxyarenes) has been achieved in water by employing the dyad Rose Bengal and hydrosoluble unmodified vitamin B12 (cyanocobalamin) as photocatalyst and co-catalyst, respectively. The reaction is performed under green LEDs irradiation and employs perfluoroalkyl bromides as perfluoroalkyl radical sources. In particular, the presence of vitamin B12 co-catalyst is found to be fundamental to elicit the formation of perfluoroalkyl radicals.
Bioinspired Photocatalysed C-H Fluoroalkylation of Arenes in Water Promoted by Native Vitamin B12 and Rose Bengal / Yerien, Damian E.; Postigo, Al; Baroncini, Massimo; Barata-Vallejo, Sebastian. - In: GREEN CHEMISTRY. - ISSN 1463-9262. - ELETTRONICO. - 23:20(2021), pp. 8147-8153. [10.1039/D1GC02654B]
Bioinspired Photocatalysed C-H Fluoroalkylation of Arenes in Water Promoted by Native Vitamin B12 and Rose Bengal
Baroncini, MassimoPenultimo
Writing – Review & Editing
;
2021
Abstract
The first perfluoroalkylation reaction of activated arenes (amino-substituted arenes and alkoxyarenes) has been achieved in water by employing the dyad Rose Bengal and hydrosoluble unmodified vitamin B12 (cyanocobalamin) as photocatalyst and co-catalyst, respectively. The reaction is performed under green LEDs irradiation and employs perfluoroalkyl bromides as perfluoroalkyl radical sources. In particular, the presence of vitamin B12 co-catalyst is found to be fundamental to elicit the formation of perfluoroalkyl radicals.| File | Dimensione | Formato | |
|---|---|---|---|
|
B12_2021MS_as_of_2207-AlSBV2.pdf
accesso aperto
Tipo:
Preprint
Licenza:
Licenza per accesso libero gratuito
Dimensione
639.04 kB
Formato
Adobe PDF
|
639.04 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
