SARS-CoV-2 is a new virus belonging to the Coronaviridae family responsible for the rapid COVID-19 spread around the world. The Cryo-EM structure of the trimeric spike (S) protein showing the exposed receptor-binding domains (RBDs) ready for interactions with the host-cell receptors as well as the docking of the spike RBD onto the ACE2 of host cells may arise as the main COVID-19 therapeutic molecular target.
Nesci, S. (2021). SARS-CoV-2 first contact: spike-ACE2 interactions in COVID-19. CHEMICAL BIOLOGY & DRUG DESIGN, 98(2), 207-211 [10.1111/cbdd.13898].
SARS-CoV-2 first contact: spike-ACE2 interactions in COVID-19
Nesci, Salvatore
Ultimo
Supervision
2021
Abstract
SARS-CoV-2 is a new virus belonging to the Coronaviridae family responsible for the rapid COVID-19 spread around the world. The Cryo-EM structure of the trimeric spike (S) protein showing the exposed receptor-binding domains (RBDs) ready for interactions with the host-cell receptors as well as the docking of the spike RBD onto the ACE2 of host cells may arise as the main COVID-19 therapeutic molecular target.File in questo prodotto:
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SARS-CoV-2 first contact Spike–ACE2 interactions in COVID-19.pdf
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