SARS-CoV-2 is a new virus belonging to the Coronaviridae family responsible for the rapid COVID-19 spread around the world. The Cryo-EM structure of the trimeric spike (S) protein showing the exposed receptor-binding domains (RBDs) ready for interactions with the host-cell receptors as well as the docking of the spike RBD onto the ACE2 of host cells may arise as the main COVID-19 therapeutic molecular target.
SARS-CoV-2 first contact: spike-ACE2 interactions in COVID-19 / Nesci, Salvatore. - In: CHEMICAL BIOLOGY & DRUG DESIGN. - ISSN 1747-0277. - STAMPA. - 98:2(2021), pp. 207-211. [10.1111/cbdd.13898]
SARS-CoV-2 first contact: spike-ACE2 interactions in COVID-19
Nesci, Salvatore
Ultimo
Supervision
2021
Abstract
SARS-CoV-2 is a new virus belonging to the Coronaviridae family responsible for the rapid COVID-19 spread around the world. The Cryo-EM structure of the trimeric spike (S) protein showing the exposed receptor-binding domains (RBDs) ready for interactions with the host-cell receptors as well as the docking of the spike RBD onto the ACE2 of host cells may arise as the main COVID-19 therapeutic molecular target.File in questo prodotto:
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SARS-CoV-2 first contact Spike–ACE2 interactions in COVID-19.pdf
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