We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humans
Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August- September 2009 / Cavrini F; Gaibani P; Longo G; Pierro AM; Rossini G; Bonilauri P; Gerundi GE; Di Benedetto F; Pasetto A; Girardis M; Dottori M; Landini MP; Sambri V. - In: EUROSURVEILLANCE. - ISSN 1025-496X. - STAMPA. - 14:(2009), pp. pii 19448-pii 19448.
Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August- September 2009.
GAIBANI, PAOLO;ROSSINI, GIADA;LANDINI, MARIA PAOLA;SAMBRI, VITTORIO
2009
Abstract
We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humansI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
