This review paper summarizes some of the most challenging issues regarding the development of electronic microsystems for the isolation, manipulation, and characterization of rare cells. Two relevant areas, namely, immunology for cancer therapy and monitoring of microbial contaminants in water, are presented as example applications which require handling of rare cells. Starting from these applications, the state of the art in electronic microsystem research is presented, and various solutions are discussed, highlighting the advantages and disadvantages of each technology and suggesting the need to integrate multiple solutions to meet the application requirements.
M. Bocchi, E. Franchi Scarselli, R. Guerrieri (2010). Electronic Microsystems for Handling of Rare Cells. IEEE TRANSACTIONS ON ELECTRON DEVICES, 57, Issue 1, January 2010, 244-255 [10.1109/TED.2009.2035026].
Electronic Microsystems for Handling of Rare Cells
BOCCHI, MASSIMO;FRANCHI SCARSELLI, ELEONORA;GUERRIERI, ROBERTO
2010
Abstract
This review paper summarizes some of the most challenging issues regarding the development of electronic microsystems for the isolation, manipulation, and characterization of rare cells. Two relevant areas, namely, immunology for cancer therapy and monitoring of microbial contaminants in water, are presented as example applications which require handling of rare cells. Starting from these applications, the state of the art in electronic microsystem research is presented, and various solutions are discussed, highlighting the advantages and disadvantages of each technology and suggesting the need to integrate multiple solutions to meet the application requirements.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.