Organometallic allylic reagents are widely used in the construction of C−C bonds by Barbier-type reactions. In this communication, we have described a photoredox Barbier allylation of aldehydes mediated by bismuth, in absence of other metals as co-reductants. Mild reaction conditions, tolerance of oxygen, and use of aqueous solvent make this photoredox methodology attractive for green and sustainable synthesis of homoallylic alcohols.
Photoredox Allylation Reactions Mediated by Bismuth in Aqueous Conditions
Gualandi A.
;Puggioli A.;Fermi A.;Bergamini G.;Cozzi P. G.
2021
Abstract
Organometallic allylic reagents are widely used in the construction of C−C bonds by Barbier-type reactions. In this communication, we have described a photoredox Barbier allylation of aldehydes mediated by bismuth, in absence of other metals as co-reductants. Mild reaction conditions, tolerance of oxygen, and use of aqueous solvent make this photoredox methodology attractive for green and sustainable synthesis of homoallylic alcohols.File in questo prodotto:
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