New chiral BINOL-based phosphate counterions have been synthesized, fully characterized, and employed in the enantioselective gold-catalyzed dearomatization of -naphthols with allenamides. A range of densely functionalized C1-allylated naphthalenones were realized under mild conditions and high levels of chemo-, regio- and stereoselectivity (ee up to 95 %).

New Chiral BINOL‐Based Phosphates for Enantioselective [Au(I)]‐Catalyzed Dearomatization of β‐Naphthols with Allenamides

Riccardo Pedrazzani
Membro del Collaboration Group
;
Juzeng An
Membro del Collaboration Group
;
Magda Monari
Conceptualization
;
Marco Bandini
Conceptualization
2021

Abstract

New chiral BINOL-based phosphate counterions have been synthesized, fully characterized, and employed in the enantioselective gold-catalyzed dearomatization of -naphthols with allenamides. A range of densely functionalized C1-allylated naphthalenones were realized under mild conditions and high levels of chemo-, regio- and stereoselectivity (ee up to 95 %).
Riccardo Pedrazzani, Juzeng An, Magda Monari, Marco Bandini
File in questo prodotto:
File Dimensione Formato  
New chiral binol.(manuscript-open)......pdf

embargo fino al 14/03/2021

Tipo: Postprint
Licenza: Creative commons
Dimensione 1.7 MB
Formato Adobe PDF
1.7 MB Adobe PDF Visualizza/Apri
New chiral binol...(supporting information)...pdf

accesso aperto

Tipo: File Supplementare
Licenza: Licenza per accesso libero gratuito
Dimensione 2.9 MB
Formato Adobe PDF
2.9 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/817850
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 5
social impact