We comment here on a recent paper in this journal, on a non-monotone transformation of biomarkers aimed at improving diagnostic accuracy. We highlight that, in a binary classification problem, the proposed transformation finds its motivation in the Neyman-Pearson lemma, so that the underlying approach is very general and it is applicable to many parametric families, other than the normal one.

Non-monotone transformation of biomarkers

Chiogna, Monica
2021

Abstract

We comment here on a recent paper in this journal, on a non-monotone transformation of biomarkers aimed at improving diagnostic accuracy. We highlight that, in a binary classification problem, the proposed transformation finds its motivation in the Neyman-Pearson lemma, so that the underlying approach is very general and it is applicable to many parametric families, other than the normal one.
STATISTICAL METHODS IN MEDICAL RESEARCH
Adimari, Gianfranco; To, Duc-Khanh; Chiogna, Monica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/817546
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