Blood transfusion is current standard-of-care for genetic forms of anemia that would be otherwise lethal and allows implementation of aggressive cytotoxic/surgical therapies developed for numerous types of cancer. In developed countries the blood supply is adequate and sporadically even in excess. However, difficulties exist in finding blood with rare phenotypes to treat alloimmunized patients and the progressive ageing of the human population predicts that blood will become scarce by 2050. These considerations establish the need for the development of techniques to generate cultured red blood cell (cRBCs) as transfusion products.

FRANCO MIGLIACCIO, A.R. (2013). Stem cell-derived erythrocytes as upcoming players in blood transfusion. ISBT SCIENCE SERIES, 8(1), 165-171 [10.1111/voxs.12048].

Stem cell-derived erythrocytes as upcoming players in blood transfusion

FRANCO MIGLIACCIO, ANNA RITA
2013

Abstract

Blood transfusion is current standard-of-care for genetic forms of anemia that would be otherwise lethal and allows implementation of aggressive cytotoxic/surgical therapies developed for numerous types of cancer. In developed countries the blood supply is adequate and sporadically even in excess. However, difficulties exist in finding blood with rare phenotypes to treat alloimmunized patients and the progressive ageing of the human population predicts that blood will become scarce by 2050. These considerations establish the need for the development of techniques to generate cultured red blood cell (cRBCs) as transfusion products.
2013
FRANCO MIGLIACCIO, A.R. (2013). Stem cell-derived erythrocytes as upcoming players in blood transfusion. ISBT SCIENCE SERIES, 8(1), 165-171 [10.1111/voxs.12048].
FRANCO MIGLIACCIO, ANNA RITA
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/797071
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