Genetic sequences are known to possess nontrivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a biologically motivated dynamics for the evolution of genetic sequences. We show that a metastable (long-lived) regime emerges in which sequences have symmetry and structure interlaced in a way that matches that of extant genomes.
Cristadoro, G., Degli Esposti, M., Altmann, E.G. (2020). Dynamics of transposable elements generates structure and symmetries in genetic sequences. PHYSICAL REVIEW RESEARCH, 2(3), 1-6 [10.1103/PhysRevResearch.2.033477].
Dynamics of transposable elements generates structure and symmetries in genetic sequences
Cristadoro, Giampaolo;Degli Esposti, Mirko;
2020
Abstract
Genetic sequences are known to possess nontrivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a biologically motivated dynamics for the evolution of genetic sequences. We show that a metastable (long-lived) regime emerges in which sequences have symmetry and structure interlaced in a way that matches that of extant genomes.File | Dimensione | Formato | |
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