Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem. © 2012 Elsevier Ireland Ltd and the Japan Neuroscience Society.
Alicandri-Ciufelli M., Aggazzotti-Cavazza E., Genovese E., Monzani D., Presutti L. (2012). Herpes zoster oticus: A clinical model for a transynaptic, reflex pathways, viral transmission hypotheses. NEUROSCIENCE RESEARCH, 74(1), 7-9 [10.1016/j.neures.2012.06.001].
Herpes zoster oticus: A clinical model for a transynaptic, reflex pathways, viral transmission hypotheses
Presutti L.Ultimo
2012
Abstract
Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem. © 2012 Elsevier Ireland Ltd and the Japan Neuroscience Society.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
