Core tip: Pancreatic acinar cell carcinoma (PACC) is a rare type of malignant pancreatic cancer. Surgery represents the first choice for treatment, but most patients experience relapse (mainly located in the liver), and there are no clear recommendations for the treatment of advanced disease. We report two cases of long-term PACC survivors treated with radiofrequency ablation in addition to chemotherapy for liver recurrence after surgery. This case report highlights the different biological behaviour of PACC compared to pancreatic adenocarcinoma and the importance of multidisciplinary treatment involving local ablative therapies, such as radiofrequency ablation, for recurrent PACC.
Long-term survival of two patients with recurrent pancreatic acinar cell carcinoma treated with radiofrequency ablation: A case report.
Di Marco MPrimo
Writing – Original Draft Preparation
;Carloni R;De Lorenzo S;Grassi E;Palloni A;Formica F;Brocchi S;Filippini DM;Golfieri R;Brandi G.
2020
Abstract
Core tip: Pancreatic acinar cell carcinoma (PACC) is a rare type of malignant pancreatic cancer. Surgery represents the first choice for treatment, but most patients experience relapse (mainly located in the liver), and there are no clear recommendations for the treatment of advanced disease. We report two cases of long-term PACC survivors treated with radiofrequency ablation in addition to chemotherapy for liver recurrence after surgery. This case report highlights the different biological behaviour of PACC compared to pancreatic adenocarcinoma and the importance of multidisciplinary treatment involving local ablative therapies, such as radiofrequency ablation, for recurrent PACC.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
