The first enantioselective method for the installation of the SCF3 group at the C-4 position of azlactones is described in the present communication under quinidinium phase transfer catalysis. The higher performance of substrates containing electron-rich 2-aryl groups at the azlactone was rationalized using DFT calculations.

Asymmetric trifluoromethylthiolation of azlactones under chiral phase transfer catalysis

Bernardi L.;
2020

Abstract

The first enantioselective method for the installation of the SCF3 group at the C-4 position of azlactones is described in the present communication under quinidinium phase transfer catalysis. The higher performance of substrates containing electron-rich 2-aryl groups at the azlactone was rationalized using DFT calculations.
2020
Sicignano M.; Rodriguez R.I.; Capaccio V.; Borello F.; Cano R.; De Riccardis F.; Bernardi L.; Diaz-Tendero S.; Della Sala G.; Aleman J.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/787201
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