Ileal Peyer's patches (PPs) are involved early during sheep scrapie infection. This study qualitatively and semi-quantitatively evaluated ileal tract and PP innervation in 29 Sarda ovines of different age, PrP genotype and scrapie status. A prominent network of fibres was detected within PPs, mainly located in interfollicular lymphoid and stromal components. Intrafollicular fibres were rarely observed, with no apparent differences between scrapie-free and scrapie-affected animals, or among ovines carrying different PrP genotypes. In adult sheep, independent of their scrapie status, nerve fibres could be detected infrequently, close to the follicle-associated epithelium. Fibres were also detected within newly formed follicles and intrafollicular microgranulomas.

MARRUCHELLA G., | LIGIOS C., | BAFFONI M.|, CANCEDDA M.G., | DEMONTIS F., | DONATUCCI G., et al. (2009). Ileal tract and Peyer's patch innervation in scrapie-free versus scrapie-affected ovines. ARCHIVES OF VIROLOGY, 154/4, 709-714 [10.1007/s00705-009-0361-5].

Ileal tract and Peyer's patch innervation in scrapie-free versus scrapie-affected ovines

CHIOCCHETTI, ROBERTO;CLAVENZANI, PAOLO;LALATTA COSTERBOSA, GIOVANNA;
2009

Abstract

Ileal Peyer's patches (PPs) are involved early during sheep scrapie infection. This study qualitatively and semi-quantitatively evaluated ileal tract and PP innervation in 29 Sarda ovines of different age, PrP genotype and scrapie status. A prominent network of fibres was detected within PPs, mainly located in interfollicular lymphoid and stromal components. Intrafollicular fibres were rarely observed, with no apparent differences between scrapie-free and scrapie-affected animals, or among ovines carrying different PrP genotypes. In adult sheep, independent of their scrapie status, nerve fibres could be detected infrequently, close to the follicle-associated epithelium. Fibres were also detected within newly formed follicles and intrafollicular microgranulomas.
2009
MARRUCHELLA G., | LIGIOS C., | BAFFONI M.|, CANCEDDA M.G., | DEMONTIS F., | DONATUCCI G., et al. (2009). Ileal tract and Peyer's patch innervation in scrapie-free versus scrapie-affected ovines. ARCHIVES OF VIROLOGY, 154/4, 709-714 [10.1007/s00705-009-0361-5].
MARRUCHELLA G.;| LIGIOS C.;| BAFFONI M.|; CANCEDDA M.G.;| DEMONTIS F.;| DONATUCCI G.;| CHIOCCHETTI R.;| CLAVENZANI P.; LALATTA-COSTERBOSA G.;|DI GUARD...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/78556
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