We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99+/-0.67 microg/mL, and the C(L)/C(P) at 2 hours after dosing was 0.34+/-0.09.
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis / Scotton P.G.; Pea F.; Giobbia M.; Baraldo M.; Vaglia A.; Furlanut M.. - In: CLINICAL INFECTIOUS DISEASES. - ISSN 1058-4838. - ELETTRONICO. - 33:9(2001), pp. e109-e111. [10.1086/323406]
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis
Pea F.;
2001
Abstract
We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99+/-0.67 microg/mL, and the C(L)/C(P) at 2 hours after dosing was 0.34+/-0.09.File in questo prodotto:
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