We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99+/-0.67 microg/mL, and the C(L)/C(P) at 2 hours after dosing was 0.34+/-0.09.
Scotton P.G., Pea F., Giobbia M., Baraldo M., Vaglia A., Furlanut M. (2001). Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis. CLINICAL INFECTIOUS DISEASES, 33(9), e109-e111 [10.1086/323406].
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis
Pea F.;
2001
Abstract
We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99+/-0.67 microg/mL, and the C(L)/C(P) at 2 hours after dosing was 0.34+/-0.09.File in questo prodotto:
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