The aim of this work was to study the variability of single nucleotide polymorphisms (SNPs) in candidate genes for litter size in Italian Large White (ILW) pig breed. We genotyped 120 sows for 10 SNPS in 10 genes detected in the literature. The results indicated that the CLGN, pDAZL and RFN4 SNPs were not segregating in the analyzed ILW while the remaining loci were polymorphic with minor allele frequency ranging from 0.10 (AFP) to 0.48 (RBP4). On the basis of the genetic variability, the investigated SNPs in the AFP, BMPR1B, CXCL10, ESR2, GNRHR, MAN2B2 and RBP4 genes, can be used as markers in association studies with litter size in ILW.
STRUTTURA GENETICA DELLA RAZZA SUINA LARGE WHITE ITALIANA IN GENI CANDIDATI PER LA PROLIFICITA’ / Dall’Olio S.; Fontanesi L.; Tognazzi L.. - In: ATTI ... CONVEGNO NAZIONALE AIPVET. - ISSN 1825-2265. - ELETTRONICO. - LXIII:(2009), pp. 436-438.
STRUTTURA GENETICA DELLA RAZZA SUINA LARGE WHITE ITALIANA IN GENI CANDIDATI PER LA PROLIFICITA’
DALL'OLIO, STEFANIA;FONTANESI, LUCA;
2009
Abstract
The aim of this work was to study the variability of single nucleotide polymorphisms (SNPs) in candidate genes for litter size in Italian Large White (ILW) pig breed. We genotyped 120 sows for 10 SNPS in 10 genes detected in the literature. The results indicated that the CLGN, pDAZL and RFN4 SNPs were not segregating in the analyzed ILW while the remaining loci were polymorphic with minor allele frequency ranging from 0.10 (AFP) to 0.48 (RBP4). On the basis of the genetic variability, the investigated SNPs in the AFP, BMPR1B, CXCL10, ESR2, GNRHR, MAN2B2 and RBP4 genes, can be used as markers in association studies with litter size in ILW.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
