The rate constants of the title reactions have been measured at various amine concentrations. The second-order kinetic constant for the amino substitution increases in a hyperbolic way as a function of the nucleophile concentration. The k3Am/k-1 ratio for each catalysed system is not a monotonic function of the X substituent. This result has been rationalized in the framework of the SB-GA (Specific Base-General Acid) mechanism of base catalysis.
Frenna V., Macaluso G., Consiglio G., Guernelli S., Spinelli D. (1999). Kinetic study of the reactions of some 5-nitro-2-(4-nitrophenoxy)-3-x-thiophenes with aniline and 4-methoxyaniline in methanol. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 64(11), 1877-1892 [10.1135/cccc19991877].
Kinetic study of the reactions of some 5-nitro-2-(4-nitrophenoxy)-3-x-thiophenes with aniline and 4-methoxyaniline in methanol
Consiglio G.;Guernelli S.;
1999
Abstract
The rate constants of the title reactions have been measured at various amine concentrations. The second-order kinetic constant for the amino substitution increases in a hyperbolic way as a function of the nucleophile concentration. The k3Am/k-1 ratio for each catalysed system is not a monotonic function of the X substituent. This result has been rationalized in the framework of the SB-GA (Specific Base-General Acid) mechanism of base catalysis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
