The construction of a hybrid metal-organo-photoredox catalyst based on the conjugation of an imidazolidinone organocatalyst and Ir(ppy)2(bipy) (ppy = 2-phenylpyridine, bipy = bipyridine) is described. The introduction of the desired organocatalyst into the bipyridine moiety is quite modular, allowing the preparation of different hybrid photocatalysts, and is realized though a simple click reaction. The hybrid photocatalysts obtained were employed in the benchmark photoredox alkylation of aldehydes. Remarkably, the conjugation of a first-generation MacMillan catalyst produces an active and stereoselective hybrid photoredox catalyst.

A supramolecular bifunctional iridium photoaminocatalyst for the enantioselective alkylation of aldehydes

Gualandi, Andrea
;
Calogero, Francesco;Martinelli, Ada;Quintavalla, Arianna;Marchini, Marianna;Ceroni, Paola
;
Lombardo, Marco
;
Cozzi, Pier Giorgio
2020

Abstract

The construction of a hybrid metal-organo-photoredox catalyst based on the conjugation of an imidazolidinone organocatalyst and Ir(ppy)2(bipy) (ppy = 2-phenylpyridine, bipy = bipyridine) is described. The introduction of the desired organocatalyst into the bipyridine moiety is quite modular, allowing the preparation of different hybrid photocatalysts, and is realized though a simple click reaction. The hybrid photocatalysts obtained were employed in the benchmark photoredox alkylation of aldehydes. Remarkably, the conjugation of a first-generation MacMillan catalyst produces an active and stereoselective hybrid photoredox catalyst.
2020
Gualandi, Andrea; Calogero, Francesco; Martinelli, Ada; Quintavalla, Arianna; Marchini, Marianna; Ceroni, Paola; Lombardo, Marco; Cozzi, Pier Giorgio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/777081
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