Melorheostosis (MEL) is a rare benign bone disorder that can be associated with several anomalies, including vascular abnormalities, nevus sebaceus, unilateral nevoid telangiectasia, linear scleroderma and hypertrichosis. We report the case of a 6-year-old patient who showed an unusual co-occurrence of bone hyperostosis and different skin lesions affecting the same side of the body: MEL, verrucous epidermal nevus, connective tissue nevus, linear scleroderma-like disorder, hyperpigmentation and hypertrichosis. The spatial co-occurrence of these conditions made us speculate as to whether they originated from a common genetic mechanism or if their co-occurrence was completely accidental.
Case of melorheostosis associated with ipsilateral verrucous epidermal nevus, linear connective tissue nevus, diffuse hyperpigmentation and hypertrichosis: A fortuitous coincidence? / Di Altobrando A.; Neri I.; Gurioli C.; Misciali C.; Baraldi C.; Pedrini E.; Gnoli M.; Tremosini M.; Sangiorgi L.; Patrizi A.. - In: JOURNAL OF DERMATOLOGY. - ISSN 0385-2407. - STAMPA. - 47:9(2020), pp. 1063-1066. [10.1111/1346-8138.15460]
Case of melorheostosis associated with ipsilateral verrucous epidermal nevus, linear connective tissue nevus, diffuse hyperpigmentation and hypertrichosis: A fortuitous coincidence?
Di Altobrando A.
;Neri I.;Gurioli C.;Misciali C.;Baraldi C.;Gnoli M.;Sangiorgi L.;Patrizi A.
2020
Abstract
Melorheostosis (MEL) is a rare benign bone disorder that can be associated with several anomalies, including vascular abnormalities, nevus sebaceus, unilateral nevoid telangiectasia, linear scleroderma and hypertrichosis. We report the case of a 6-year-old patient who showed an unusual co-occurrence of bone hyperostosis and different skin lesions affecting the same side of the body: MEL, verrucous epidermal nevus, connective tissue nevus, linear scleroderma-like disorder, hyperpigmentation and hypertrichosis. The spatial co-occurrence of these conditions made us speculate as to whether they originated from a common genetic mechanism or if their co-occurrence was completely accidental.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.