A process for the epoxidation of 17-oxo-15,16-methylene steroids, in particular of drospirenone precursors, comprising the use of sulfoxonium ylides, in particular of dimethylsulfoxonium methyl ylide. The process allows to prepare in good yields 17-spiro epoxides, which can be easily transformed into 17-spironolacto-steroids.
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides / Cabri W; Alpegiani; Benedetti; F.; M.Rodriquez; Botta; C.. - (2007).
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides
Cabri W;
2007
Abstract
A process for the epoxidation of 17-oxo-15,16-methylene steroids, in particular of drospirenone precursors, comprising the use of sulfoxonium ylides, in particular of dimethylsulfoxonium methyl ylide. The process allows to prepare in good yields 17-spiro epoxides, which can be easily transformed into 17-spironolacto-steroids.File in questo prodotto:
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