The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.
An Improved Process for The Preparation of Ribociclib and its Salts / Sokhi; S.S.; Singh; G.; Lahiri; S.; Pandey; M.K.; Tiwari; R.N.; Shukla; S.; Musmade; S.M.; Dua; H.; Cabri W. - (2019).
An Improved Process for The Preparation of Ribociclib and its Salts
Cabri W
2019
Abstract
The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.File in questo prodotto:
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