Tooth enamel does not contain living cells and is not capable of regenerating, therefore, any damage caused is irreversible. New biomimetic carbonate-hydroxyapatite nanocrystals (CHA) have been designed and synthesized in order to obtain a remineralization of the altered enamel surfaces. For structure, nano dimensions and morphology, synthesized CHA mimic tooth apatite crystals and their chemical composition resemble closely to that of natural mineral that makes up dentine and tooth enamel. CHA can penetrate into the smallest teeth cracks and flaws and, thanks to their tailored biomimetic characteristics, chemically bind themselves on the natural apatite surface of enamel and dentine remineralizing and repairing the teeth. Scanning and transmission electron microscopy, Xray diffraction, X-ray photoemission spectroscopy and infrared spectral analysis have been utilized to investigate in vitro and in vivo the sound capacity of synthetic biomimetic carbonate-hydroxyapatite nanocrystals to induce enamel and dentine remineralization. This finding has an impact on several disorders. The biomimetic mineral coating, which progressively fills the surface scratches, covers and safeguards the enamel structure by contrasting the acid and bacteria attacks as well as protecting against sensitivity by covering dentinal tubules.
N. roveri (2009). Syntetic Biomimetic Hydroxyapatite for dental health. s.l : s.n.
Syntetic Biomimetic Hydroxyapatite for dental health
ROVERI, NORBERTO
2009
Abstract
Tooth enamel does not contain living cells and is not capable of regenerating, therefore, any damage caused is irreversible. New biomimetic carbonate-hydroxyapatite nanocrystals (CHA) have been designed and synthesized in order to obtain a remineralization of the altered enamel surfaces. For structure, nano dimensions and morphology, synthesized CHA mimic tooth apatite crystals and their chemical composition resemble closely to that of natural mineral that makes up dentine and tooth enamel. CHA can penetrate into the smallest teeth cracks and flaws and, thanks to their tailored biomimetic characteristics, chemically bind themselves on the natural apatite surface of enamel and dentine remineralizing and repairing the teeth. Scanning and transmission electron microscopy, Xray diffraction, X-ray photoemission spectroscopy and infrared spectral analysis have been utilized to investigate in vitro and in vivo the sound capacity of synthetic biomimetic carbonate-hydroxyapatite nanocrystals to induce enamel and dentine remineralization. This finding has an impact on several disorders. The biomimetic mineral coating, which progressively fills the surface scratches, covers and safeguards the enamel structure by contrasting the acid and bacteria attacks as well as protecting against sensitivity by covering dentinal tubules.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.