The tear film is a pre-corneal optical interface with refractive functions for the eye and supervises important protective properties against environmental stress. Many systemic and neurodegenerative diseases affecting the eyes such as Rheumatoid arthritis, Sjogren’s syndrome, type 2 diabetes, Alzheimer’s disease, Multiple sclerosis and Parkinson’s disease leave imprints in the tear film. These imprints, namely the biomarkers, have great value in the diagnosis and prognosis of the systemic and ocular surface diseases (OSD). Tear analysis also offers interesting perspectives for patient stratification in clinical trial research. The purpose of this SIG will not only be to introduce sound and evidence based methods and promising tear/ocular surface novel biomarkers with potential to diagnose systemic and OSD but also generate discussion for possible consensus in the current and future application of “Omics” or Microfluidic-based technologies. Panelists and Speakers will share their experience in translational research and clinical practice with the audience, with the aim to forward the knowledge that tear analysis deserves a place in the patients’ management in the modern Eye Clinic.
TEAR BIOMARKERS OF OCULAR SURFACE DISEASES IN THE CLINIC- A Special Interest Group
Versura, P
;
2019
Abstract
The tear film is a pre-corneal optical interface with refractive functions for the eye and supervises important protective properties against environmental stress. Many systemic and neurodegenerative diseases affecting the eyes such as Rheumatoid arthritis, Sjogren’s syndrome, type 2 diabetes, Alzheimer’s disease, Multiple sclerosis and Parkinson’s disease leave imprints in the tear film. These imprints, namely the biomarkers, have great value in the diagnosis and prognosis of the systemic and ocular surface diseases (OSD). Tear analysis also offers interesting perspectives for patient stratification in clinical trial research. The purpose of this SIG will not only be to introduce sound and evidence based methods and promising tear/ocular surface novel biomarkers with potential to diagnose systemic and OSD but also generate discussion for possible consensus in the current and future application of “Omics” or Microfluidic-based technologies. Panelists and Speakers will share their experience in translational research and clinical practice with the audience, with the aim to forward the knowledge that tear analysis deserves a place in the patients’ management in the modern Eye Clinic.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
