Alirocumab and evolocumab are fully human monoclonal antibodies that inhibit proprotein convertase subtilisinekexin type 9 [iPCSK9]. These agents reduce the risk of cardiovascular and limb events in statin-treated subjects [1,2]. However, the effect of iPCSK9 on arterial stiffness has not yet been reported. In this report, we present data from two patients who experienced an impressive improvement in carotid-femoral pulse wave velocity [cfPWV] after short-term treatment with iPCSK9

Cicero, A., Toth, P.p., Fogacci, F., Virdis, A., Borghi, C. (2019). Improvement in arterial stiffness after short-term treatment with PCSK9 inhibitors. NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 29(5), 527-529 [10.1016/j.numecd.2019.01.010].

Improvement in arterial stiffness after short-term treatment with PCSK9 inhibitors.

Cicero A;Borghi C
2019

Abstract

Alirocumab and evolocumab are fully human monoclonal antibodies that inhibit proprotein convertase subtilisinekexin type 9 [iPCSK9]. These agents reduce the risk of cardiovascular and limb events in statin-treated subjects [1,2]. However, the effect of iPCSK9 on arterial stiffness has not yet been reported. In this report, we present data from two patients who experienced an impressive improvement in carotid-femoral pulse wave velocity [cfPWV] after short-term treatment with iPCSK9
2019
Cicero, A., Toth, P.p., Fogacci, F., Virdis, A., Borghi, C. (2019). Improvement in arterial stiffness after short-term treatment with PCSK9 inhibitors. NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 29(5), 527-529 [10.1016/j.numecd.2019.01.010].
Cicero, A; Toth, Pp; Fogacci, F; Virdis, A; Borghi, C
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/724240
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