Charged Particle Therapy (CPT) is a powerful radiotherapy technique for the treatment of deep-seated tumours characterized by a large dose released in the Bragg peak area (corresponding to the tumour region) and a small dose delivered to the surrounding healthy tissues. The precise measurement of the fragments produced in the nuclear interactions of charged particle beams with patient tissues is a crucial task to improve the clinical treatment plans. The FOOT (FragmentatiOn Of Target) experiment is an international project, funded by the Istituto Nazionale di Fisica Nucleare (INFN), aimed to study the dose released by the tissues and particle beams fragmentation. The target (16O, 12C) fragmentation induced by 150-400 MeV/n proton beams will be studied via the inverse kinematic approach, where 16O and 12C therapeutic beams collide on graphite and hydrocarbon target to provide the cross section on Hydrogen. A table-top detector is being developed and it includes a drift chamber as a beam monitor upstream of the target to measure the beam direction, a magnetic spectrometer based on silicon pixel and strip detectors, a scintillating crystal calorimeter able to stop the heavier produced fragments, and a ΔE detector, with TOF capability, for the particle identification. A setup based on the concept of the “Emulsion Cloud Chamber”, coupled with the interaction region of the electronic FOOT setup, will complement the physics program by measuring lighter charged fragments to extend the angular acceptance up to about 70 degrees. In this work, the experimental design and the requirements of the FOOT experiment will be discussed and preliminary results on the emulsion spectrometer tests will be presented.

THE FOOT EXPERIMENT: FRAGMENTATION MEASUREMENTS IN PARTICLE THERAPY

S. Biondi;M. Franchini;M. Garbini;A. Mengarelli;R. Ridolfi;G. Sartorelli;M. Selvi;M. Villa;A. Zoccoli
2019

Abstract

Charged Particle Therapy (CPT) is a powerful radiotherapy technique for the treatment of deep-seated tumours characterized by a large dose released in the Bragg peak area (corresponding to the tumour region) and a small dose delivered to the surrounding healthy tissues. The precise measurement of the fragments produced in the nuclear interactions of charged particle beams with patient tissues is a crucial task to improve the clinical treatment plans. The FOOT (FragmentatiOn Of Target) experiment is an international project, funded by the Istituto Nazionale di Fisica Nucleare (INFN), aimed to study the dose released by the tissues and particle beams fragmentation. The target (16O, 12C) fragmentation induced by 150-400 MeV/n proton beams will be studied via the inverse kinematic approach, where 16O and 12C therapeutic beams collide on graphite and hydrocarbon target to provide the cross section on Hydrogen. A table-top detector is being developed and it includes a drift chamber as a beam monitor upstream of the target to measure the beam direction, a magnetic spectrometer based on silicon pixel and strip detectors, a scintillating crystal calorimeter able to stop the heavier produced fragments, and a ΔE detector, with TOF capability, for the particle identification. A setup based on the concept of the “Emulsion Cloud Chamber”, coupled with the interaction region of the electronic FOOT setup, will complement the physics program by measuring lighter charged fragments to extend the angular acceptance up to about 70 degrees. In this work, the experimental design and the requirements of the FOOT experiment will be discussed and preliminary results on the emulsion spectrometer tests will be presented.
A. Alexandrov, L. Alunni Solestizi, G. Ambrosi, S. Argirò, R. Arteche Diaz, N. Bartosik, G. Battistoni, N. Belcari, E. Bellinzona, S. Bianucci, S. Biondi, M. G. Bisogni, G. Bruni, N. Camarlinghi, P. Carra, P. Cerello, E. Ciarrocchi, A. Clozza, S. Colombi, G. De Lellis, A. Del Guerra, M. De Simoni, A. Di Crescenzo, M. Donetti, Y. Dong, M. Durante, A. Embriaco, M. Emde, R. Faccini, V. Ferrero, F. Ferroni, E. Fiandrini, C. Finck, E. Fiorina, M. Fischetti, M. Francesconi, M. Franchini, G. Galati, L. Galli, M. Garbini, V. Gentile, G. Giraudo, R. Hetzel, E. Iarocci, M. Ionica, K. Kanxheri, A. C. Kraan, V. Lante, A. Lauria, C. La Tessa, E. Lopez Torres, M. Marafini, I. Mattei, A. Mengarelli, R. Mirabelli, A. Moggi, M. C. Montesi, M. C. Morone, M. Morrocchi, S. Muraro, L. Narici, A. Pastore, N. Pastrone, V. Patera, F. Pennazio, P. Placidi, M. Pullia, F. Raffaeli, L. Ramello, R. Ridolfi, V. Rosso, M. Rovituso, C. Sanelli, A. Sarti, G. Sartorelli, O. Sato, S. Savazzi, L. Scavarda, A. Schiavi, C. Schuy, E. Scifoni, A. Sciubba, A. Sécher, M. Selvi, L. Servoli, G. Silvestre, M. Sitta, R. Spighi, E. Spiriti, G. Sportelli, A. Stahl, V. Tioukov, S. Tommasini, F. Tommasino, G. Traini, S. M. Valle, M. Vanstalle, M. Villa, U. Webe, A. Zoccoli
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/721852
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