Introduction: Multiple organ failure has been considered a contraindication for noninvasive ventilation (NIV). Materials and methods: We described the outcome of Do-not-Intubate (DNI) patients with acute respiratory failure, treated with NIV and, subsequently, necessitating renal replacement therapy (RRT). Results and discussion: Seven patients admitted to our Respiratory Intensive Care Unit, developed Acute Kidney Injury (AKI) during NIV treatment and received RRT for 12.8 ± 8 days together with NIV. All the patients but one, discontinued renal support because they regained a satisfactory urinary output; nevertheless mortality rate was high (71%). Conclusion: Our data suggest that RRT could be feasible together with NIV. RRT was associated with an acute improvement in renal function but did not modify the mortality rate.
Titolo: | Noninvasive ventilation and renal replacement therapy in do-not-intubate order critically ill patients: A brief report | |
Autore/i: | Catalanotti, Vito; Pisani, Lara; Betti, Sara; Bensai, Serena; PREDILETTO, IRENE; Fasano, Luca; Nava, Stefano | |
Autore/i Unibo: | ||
Anno: | 2019 | |
Rivista: | ||
Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/crj.13023 | |
Abstract: | Introduction: Multiple organ failure has been considered a contraindication for noninvasive ventilation (NIV). Materials and methods: We described the outcome of Do-not-Intubate (DNI) patients with acute respiratory failure, treated with NIV and, subsequently, necessitating renal replacement therapy (RRT). Results and discussion: Seven patients admitted to our Respiratory Intensive Care Unit, developed Acute Kidney Injury (AKI) during NIV treatment and received RRT for 12.8 ± 8 days together with NIV. All the patients but one, discontinued renal support because they regained a satisfactory urinary output; nevertheless mortality rate was high (71%). Conclusion: Our data suggest that RRT could be feasible together with NIV. RRT was associated with an acute improvement in renal function but did not modify the mortality rate. | |
Data stato definitivo: | 2020-01-30T15:13:27Z | |
Appare nelle tipologie: | 1.01 Articolo in rivista |