We design an agent based Monte Carlo model of antibiotics research and development (R&D) to explore the effects of the policy intervention known as Market Entry Reward (MER) on the likelihood that an antibiotic entering pre-clinical development reaches the market. By means of sensitivity analysis we explore the interaction between the MER and four key parameters: projected net revenues, R&D costs, venture capitalists discount rates, and large pharmaceutical organizations' financial thresholds. We show that improving revenues may be more efficient than reducing costs, and thus confirm that this pull-based policy intervention effectively stimulates antibiotics R&D.

Okhravi C., Callegari S., McKeever S., Kronlid C., Baraldi E., Lindahl O., et al. (2018). Simulating market entry rewards for antibiotics development. THE JOURNAL OF LAW, MEDICINE & ETHICS, 46(1_suppl), 32-42 [10.1177/1073110518782913].

Simulating market entry rewards for antibiotics development

Ciabuschi F.
2018

Abstract

We design an agent based Monte Carlo model of antibiotics research and development (R&D) to explore the effects of the policy intervention known as Market Entry Reward (MER) on the likelihood that an antibiotic entering pre-clinical development reaches the market. By means of sensitivity analysis we explore the interaction between the MER and four key parameters: projected net revenues, R&D costs, venture capitalists discount rates, and large pharmaceutical organizations' financial thresholds. We show that improving revenues may be more efficient than reducing costs, and thus confirm that this pull-based policy intervention effectively stimulates antibiotics R&D.
2018
Okhravi C., Callegari S., McKeever S., Kronlid C., Baraldi E., Lindahl O., et al. (2018). Simulating market entry rewards for antibiotics development. THE JOURNAL OF LAW, MEDICINE & ETHICS, 46(1_suppl), 32-42 [10.1177/1073110518782913].
Okhravi C.; Callegari S.; McKeever S.; Kronlid C.; Baraldi E.; Lindahl O.; Ciabuschi F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/715022
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