Cardiac allograft vasculopathy (CAV) is the major cause limiting long term graft survival after heart transplantation (HT), and is characterized by changes in coronary artery geometry, such as intimal thickening and vessel remodeling. Given the limited strategies available to reduce its impact on outcome, early diagnosis of CAV - for which intravascular ultrasound (IVUS) is the gold standard - is crucial to appropriately modulate therapy and to reduce contributing risk factors. However, a highly reproducible image-analysis method is required to capture the complex mechanisms beyond CAV - related changes in coronary geometry.
V D'Errico, L Potena, D Fiore, F Fabbri, F Grigioni, G Magnani, et al. (2008). Reproducibility of IVUS Measurements in Heart Transplant Recipients: Increased Quality of Data by Using Dedicated Software for Image Analysis. Los Alamitos, CA : IEEE [10.1109/CIC.2008.4749097].
Reproducibility of IVUS Measurements in Heart Transplant Recipients: Increased Quality of Data by Using Dedicated Software for Image Analysis
POTENA, LUCIANO;GRIGIONI, FRANCESCO;MAGNANI, GAIA;ORTOLANI, PAOLO;CORAZZA, IVAN;ZANNOLI, ROMANO;BRANZI, ANGELO;FIORE, DANIELA;FABBRI, FRANCESCA;BIANCHI, ISIDORO GIORGIO
2008
Abstract
Cardiac allograft vasculopathy (CAV) is the major cause limiting long term graft survival after heart transplantation (HT), and is characterized by changes in coronary artery geometry, such as intimal thickening and vessel remodeling. Given the limited strategies available to reduce its impact on outcome, early diagnosis of CAV - for which intravascular ultrasound (IVUS) is the gold standard - is crucial to appropriately modulate therapy and to reduce contributing risk factors. However, a highly reproducible image-analysis method is required to capture the complex mechanisms beyond CAV - related changes in coronary geometry.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
