Purpose: The purpose of this article was to evaluate the potential association between sociodemographic factors with clinical characteristics, vision-related quality of life (QoL), and glaucoma-related symptoms scores in a large cohort of primary open-angle glaucoma patients. Materials and Methods: Multicenter, cross-sectional study involving academic and nonacademic centers. Previously diagnosed primary open-angle glaucoma patients aged >18 years were enrolled. At baseline, information on demographic characteristics, social, medical and ocular history, clinical presentation and treatments was collected. Vision-related QoL was evaluated by means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), while glaucoma-related symptoms were evaluated using the Glaucoma Symptom Scale (GSS) questionnaire. The associations between sociodemographic factors with clinical characteristics (mean deviation, pattern standard deviation, best-corrected visual acuity), NEI-VFQ-25, and GSS scores were evaluated by means of univariate and multivariate general linear models. Results: A total of 3227 patients were enrolled. Older age and male sex were significantly associated with lower mean deviation (P<0.01) and higher pattern standard deviation (P<0.01), whereas older age was associated with lower best-corrected visual acuity (P<0.01). The composite GSS score was related to age (P=0.02), sex (P<0.01), employment (P=0.01), and profession (P=0.04), while the total NEI-VFQ-25 score was associated with sex (P<0.01), marital status (P=0.02), and employment (P=0.02). Conclusions: Age and sex were significantly associated with almost all indicators of glaucoma severity at baseline. Other variables, such as employment, profession, and marital status were significantly associated with vision-related QoL scores.

Influence of sociodemographic factors on disease characteristics and vision-related quality of life in primary open-angle glaucoma patients: The Italian primary open angle glaucoma study (IPOAGS)

L Fontana;E Campos;C Gizzi;G Giannaccare
Membro del Collaboration Group
;
2018

Abstract

Purpose: The purpose of this article was to evaluate the potential association between sociodemographic factors with clinical characteristics, vision-related quality of life (QoL), and glaucoma-related symptoms scores in a large cohort of primary open-angle glaucoma patients. Materials and Methods: Multicenter, cross-sectional study involving academic and nonacademic centers. Previously diagnosed primary open-angle glaucoma patients aged >18 years were enrolled. At baseline, information on demographic characteristics, social, medical and ocular history, clinical presentation and treatments was collected. Vision-related QoL was evaluated by means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), while glaucoma-related symptoms were evaluated using the Glaucoma Symptom Scale (GSS) questionnaire. The associations between sociodemographic factors with clinical characteristics (mean deviation, pattern standard deviation, best-corrected visual acuity), NEI-VFQ-25, and GSS scores were evaluated by means of univariate and multivariate general linear models. Results: A total of 3227 patients were enrolled. Older age and male sex were significantly associated with lower mean deviation (P<0.01) and higher pattern standard deviation (P<0.01), whereas older age was associated with lower best-corrected visual acuity (P<0.01). The composite GSS score was related to age (P=0.02), sex (P<0.01), employment (P=0.01), and profession (P=0.04), while the total NEI-VFQ-25 score was associated with sex (P<0.01), marital status (P=0.02), and employment (P=0.02). Conclusions: Age and sex were significantly associated with almost all indicators of glaucoma severity at baseline. Other variables, such as employment, profession, and marital status were significantly associated with vision-related QoL scores.
2018
I Riva, L Legramandi, A Katsanos, F Oddone, E Rulli, G Roberti, L Quaranta, Italian Study Group on QoL in Glaucoma: L Varano, T Carchedi, S Talarico, F Parravano, I Motolese, SA Bagaglia, GCM Rossi, S Lateri, L Bossolesi, L Carmassi, T Rolle, R Piccini, R Ratiglia, A Rossi, S Gandolfi, V Tagliavini, N Ungaro, M Fossarello, A Cucca, I Zucca, M Uva, E Bonacci, G Cardarella, D Tognetto, O Vattovani, P Vallon, F Iannacone, L Fontana, S Marchi, GL Manni, D Jannetta, L Rossetti, E Maggiolo, O Oneta, C Sborgia, F Cantatore, L Mastropasqua, L Agnifili, E Campos, C Gizzi, G Giannaccare, V Pucci, M Cassamali, C Costagliola, C Traverso, R Scotto, M Musolino, L Landi, A Bagnis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/711692
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