The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor-host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.
De Giovanni, C., Nicoletti, G., Landuzzi, L., Palladini, A., Lollini, P., Nanni, P. (2019). Bioprofiling TS/A Murine Mammary Cancer for a Functional Precision Experimental Model. CANCERS, 11(12), 1-20 [10.3390/cancers11121889].
Bioprofiling TS/A Murine Mammary Cancer for a Functional Precision Experimental Model
De Giovanni, Carla;Landuzzi, Lorena;Palladini, Arianna;Lollini, Pier-Luigi;Nanni, Patrizia
2019
Abstract
The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor-host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.| File | Dimensione | Formato | |
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