The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor-host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.

Bioprofiling TS/A Murine Mammary Cancer for a Functional Precision Experimental Model

De Giovanni, Carla;Landuzzi, Lorena;Palladini, Arianna;Lollini, Pier-Luigi;Nanni, Patrizia
2019

Abstract

The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor-host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.
De Giovanni, Carla; Nicoletti, Giordano; Landuzzi, Lorena; Palladini, Arianna; Lollini, Pier-Luigi; Nanni, Patrizia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/708257
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