Substituted hydroxy-benzofurans are easily accessible by treatment of resorcinols and 1,2-diaza-1,3-dienes (DDs) under acidic conditions. The reaction happens through an uncommon Michael reaction between aromatic derivatives as aromatic C(sp2)-H nucleophiles and DDs as acceptors. Also, the behavior of different phenols and 2-naphthol was investigated.
Metal and oxidant-free Brønsted acid-mediated cascade reaction to substituted benzofurans / Mari G.; Ciccolini C.; De Crescentini L.; Favi G.; Santeusanio S.; Mancinelli M.; Mantellini F.. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - ELETTRONICO. - 84:17(2019), pp. 10814-10824. [10.1021/acs.joc.9b01363]
Metal and oxidant-free Brønsted acid-mediated cascade reaction to substituted benzofurans
Mancinelli M.;
2019
Abstract
Substituted hydroxy-benzofurans are easily accessible by treatment of resorcinols and 1,2-diaza-1,3-dienes (DDs) under acidic conditions. The reaction happens through an uncommon Michael reaction between aromatic derivatives as aromatic C(sp2)-H nucleophiles and DDs as acceptors. Also, the behavior of different phenols and 2-naphthol was investigated.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
