As pointed out by Gu et al. (Science 2019) in mammalian mitochondria, the H-shaped tetrameric structure of the ATP synthase, the cell powerhouse, consists of two V-shaped dimers linked by two IF1 in antiparallel arrangement. This supramolecular structure reveals new functional/structural roles of the enzyme complex in mitochondria.
Nesci S., Pagliarani A. (2019). Emerging Roles for the Mitochondrial ATP Synthase Supercomplexes. TRENDS IN BIOCHEMICAL SCIENCES, 44(10), 821-823 [10.1016/j.tibs.2019.07.002].
Emerging Roles for the Mitochondrial ATP Synthase Supercomplexes
Nesci S.;Pagliarani A.
2019
Abstract
As pointed out by Gu et al. (Science 2019) in mammalian mitochondria, the H-shaped tetrameric structure of the ATP synthase, the cell powerhouse, consists of two V-shaped dimers linked by two IF1 in antiparallel arrangement. This supramolecular structure reveals new functional/structural roles of the enzyme complex in mitochondria.File in questo prodotto:
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Nesci_TIBS_2019_postprint.pdf
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