Polypharmacology has expanded enormously over the last ten years, with several multitarget drugs (MTDs) already in the market. This Viewpoint provides a basis for a discussion about the critical need to develop MTDs in a more rationale and conscious way. A checklist to maximize success in polypharmacology is proposed.
Bolognesi M.L. (2019). Harnessing Polypharmacology with Medicinal Chemistry. ACS MEDICINAL CHEMISTRY LETTERS, 10(3), 273-275 [10.1021/acsmedchemlett.9b00039].
Harnessing Polypharmacology with Medicinal Chemistry
Bolognesi M. L.
2019
Abstract
Polypharmacology has expanded enormously over the last ten years, with several multitarget drugs (MTDs) already in the market. This Viewpoint provides a basis for a discussion about the critical need to develop MTDs in a more rationale and conscious way. A checklist to maximize success in polypharmacology is proposed.File in questo prodotto:
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