Background: Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma. Methods: We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study. Results: Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women. Conclusions: Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes. © 2015 Cancer Research UK. All rights reserved.

Costas, L., Infante-Rivard, C., Zock, J., Van Tongeren, M., Boffetta, P., Cusson, A., et al. (2015). Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study. BRITISH JOURNAL OF CANCER, 112(7), 1251-1256 [10.1038/bjc.2015.83].

Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study

Boffetta, P.;
2015

Abstract

Background: Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma. Methods: We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study. Results: Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women. Conclusions: Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes. © 2015 Cancer Research UK. All rights reserved.
2015
Costas, L., Infante-Rivard, C., Zock, J., Van Tongeren, M., Boffetta, P., Cusson, A., et al. (2015). Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study. BRITISH JOURNAL OF CANCER, 112(7), 1251-1256 [10.1038/bjc.2015.83].
Costas, L.; Infante-Rivard, C.; Zock, J.-P.; Van Tongeren, M.; Boffetta, P.; Cusson, A.; Robles, C.; Casabonne, D.; Benavente, Y.; Becker, N.; Brennan...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/672251
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