Background: Although the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population. Methods: We conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders. Results: We observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ≥1 time/year (Ptrend <.001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ≥5 missing teeth compared with <5 missing teeth of 1.49 (95% CI 1.08-2.04). Combining multiple oral hygiene indicators, poor oral hygiene scores increased head and neck cancer risk. Conclusion: Poor oral hygiene may increase head and neck cancer risk in the Chinese population. Therefore, improving oral hygiene may contribute to reducing the head and neck cancer risk in the Chinese population. © 2017 Wiley Periodicals, Inc.
Impact of oral hygiene on head and neck cancer risk in a Chinese population / Kawakita, D. and Lee, Y.-C.A. and Li, Q. and Chen, Y. and Chen, C.-J. and Hsu, W.-L. and Lou, P.-J. and Zhu, C. and Pan, J. and Shen, H. and Ma, H. and Cai, L. and He, B. and Wang, Y. and Zhou, X. and Ji, Q. and Zhou, B. and Wu, W. and Ma, J. and Boffetta, P. and Zhang, Z.-F. and Dai, M. and Hashibe, M.. - In: HEAD & NECK. - ISSN 1043-3074. - ELETTRONICO. - 39:12(2017), pp. 2549-2557. [10.1002/hed.24929]
Impact of oral hygiene on head and neck cancer risk in a Chinese population
Boffetta, P.;
2017
Abstract
Background: Although the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population. Methods: We conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders. Results: We observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ≥1 time/year (Ptrend <.001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ≥5 missing teeth compared with <5 missing teeth of 1.49 (95% CI 1.08-2.04). Combining multiple oral hygiene indicators, poor oral hygiene scores increased head and neck cancer risk. Conclusion: Poor oral hygiene may increase head and neck cancer risk in the Chinese population. Therefore, improving oral hygiene may contribute to reducing the head and neck cancer risk in the Chinese population. © 2017 Wiley Periodicals, Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
