The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors propose the creation of a network of networks that include groups of investigators collecting data for human genome epidemiology research. Twenty-three networks of investigators addressing specific diseases or research topics and representing several hundreds of teams have already joined this initiative. For each field, the authors are currently creating a core registry of teams already participating in the respective network. A wider international registry will include all other teams also working in the same field. Independent investigators are invited to join the registries and existing networks and to join forces in creating additional ones as needed. The network of networks aims to register these networks, teams, and investigators; be a resource for information about or connections to the many networks; offer methodological support; promote sound design and standardization of analytical practices; generate inclusive overviews of fields at large; facilitate rapid confirmation of findings; and avoid duplication of effort. Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health All rights reserved.
A network of investigator networks in human genome epidemiology / Ioannidis, J.P.A.; Bernstein, J.; Boffetta, P.; Danesh, J.; Dolan, S.; Hartge, P.; Hunter, D.; Inskip, P.; Jarvelin, M.-R.; Little, J.; Maraganore, D.M.; Newton Bishop, J.A.; O'Brien, T.R.; Petersen, G.; Riboli, E.; Seminara, D.; Taioli, E.; Uitterlinden, A.G.; Vineis, P.; Winn, D.M.; Salanti, G.; Higgins, J.P.T.; Khoury, M.J.. - In: AMERICAN JOURNAL OF EPIDEMIOLOGY. - ISSN 0002-9262. - ELETTRONICO. - 162:4(2005), pp. 302-304. [10.1093/aje/kwi201]
A network of investigator networks in human genome epidemiology
Boffetta, P.;
2005
Abstract
The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors propose the creation of a network of networks that include groups of investigators collecting data for human genome epidemiology research. Twenty-three networks of investigators addressing specific diseases or research topics and representing several hundreds of teams have already joined this initiative. For each field, the authors are currently creating a core registry of teams already participating in the respective network. A wider international registry will include all other teams also working in the same field. Independent investigators are invited to join the registries and existing networks and to join forces in creating additional ones as needed. The network of networks aims to register these networks, teams, and investigators; be a resource for information about or connections to the many networks; offer methodological support; promote sound design and standardization of analytical practices; generate inclusive overviews of fields at large; facilitate rapid confirmation of findings; and avoid duplication of effort. Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
