Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial “adamantinoma-like” basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.
Gambarotti, M., Righi, A., Frisoni, T., Donati, D., Vanel, D., Sbaraglia, M., et al. (2017). Dedifferentiated chondrosarcoma with “adamantinoma-like” features: A case report and review of literature. PATHOLOGY RESEARCH AND PRACTICE, 213(6), 698-701 [10.1016/j.prp.2017.04.019].
Dedifferentiated chondrosarcoma with “adamantinoma-like” features: A case report and review of literature
Frisoni, T.;Donati, D.;Vanel, D.;
2017
Abstract
Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial “adamantinoma-like” basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
